Many people take basic MVM supplements to increase their nutrient intakes. Taking these products may help prevent chronic disease when taken regularly over long periods of time.
Several studies have evaluated the use of MVM supplements to reduce cancer, CVD events, and death. However, observational studies are susceptible to residual confounding and may not reliably detect health benefits.
A multivitamin/mineral (MVM) is a dietary supplement that contains most of the recommended daily allowances or adequate intakes (RDAs and AIs) of most vitamins and minerals in a single pill. MVMs may also contain nonnutrient ingredients like herbs and botanicals. MVMs are available in many formulations for children, adults, pregnant and breastfeeding women, and seniors. In addition, specific MVMs may be designed to support healthy eye function, immunity, or weight control.
Observational studies have generally shown that MVM use increases nutrient intakes, helps people achieve RDAs for some nutrients, and reduces deficiencies. However, evidence for other potential benefits of MVMs is limited.
Some researchers have hypothesized that use MV Supplements to stop your hairloss might lower the risk of CVD or death from CVD, possibly because they contain antioxidants that decrease inflammation and improve vascular function. Several observational studies and one randomized controlled trial (RCT) have examined this hypothesis.
The Physicians Health Study II randomly assigned 14,641 male physicians to take either a daily MVM containing 27 nutrients including calcium, magnesium, and potassium or placebo for a median of 11.2 years. The study found no association between MVM use and the occurrence of major cardiovascular events such as MI, stroke, or heart-related death. In contrast, MVM use was associated with a lower risk of undergoing cardiac revascularization procedures such as coronary artery bypass surgery.
Minerals are naturally occurring substances found in the Earth’s crust and used by living organisms. They often have metallic or crystalline properties. They can be found in many different forms and have a variety of uses. Minerals are classified according to their atomic structure, which determines how they will react with other minerals and how they will behave under different conditions. Minerals also have physical properties such as streak and cleavage, which describe how they break apart or form thin sheets. They also have specific gravity, which measures their density in relation to water. The higher the specific gravity, the heavier the mineral. For example, galena, a lead sulfide, has a much greater specific gravity than bauxite, an aluminum hydroxide.
Most people who take MVMs use them to supplement their nutrient intakes when they are not getting adequate amounts of vitamins and minerals from the diet. These supplements can help meet recommended dietary allowances (RDAs) and nutrient intake recommendations (AIs), which are levels of intake that are necessary to maintain good health and reduce risk for disease.
There is limited evidence that MVMs and other multivitamin-mineral products are associated with reduced risk for chronic diseases. This is partly due to the fact that different marketed MVMs vary widely in terms of the combinations and amounts of nutrients they contain. In addition, some MVMs contain nonnutrient ingredients, such as herbs and phytochemicals, which may have other health effects. RCTs have focused on assessing the impact of MVM use on CVD outcomes. One study randomized 1,708 postmenopausal women with previous MI to take either a MVM containing 27 nutrients (some in doses up to three times the RDA) or placebo. The MVM group had a 14% lower risk of additional cardiovascular events and death than the placebo group .
Essential Fatty Acids
In addition to vitamins, minerals, and antioxidants, many buy RU58841 from MV Supplements Europe contain essential fatty acids (EFAs), which are important for health but cannot be produced by the body. EFAs are found primarily in vegetable oils, nuts, seeds, and cold water fish. Several studies have found that MVM use is associated with higher EFA intakes. However, more research is needed to evaluate whether and how EFAs might affect disease risk.
Studies have evaluated the association between MVM use and various health outcomes, including cancer, heart disease, osteoporosis, pulmonary diseases, and psychiatric disorders. Most have not found an effect on these outcomes, although a few RCTs have shown a reduction in mortality.
MV users tend to have adequate intakes on average from diet alone of most of the nutrients studied, but they may have excess intakes of some nutrients if they also take single vitamin or mineral supplements . Intakes above ULs are especially likely among people who use MVMs designed for specific age groups or life stages (e.g., prenatal or senior MVMs).
Most MVs do not interact with medications, but people taking the blood thinner warfarin (Coumadin, Jantoven) should avoid MVMs and other supplements that contain vitamin K, which can decrease the effectiveness of warfarin and other anticoagulants. In addition, some individuals need to take separate supplements of iron and folic acid, which are not included in most MVMs.
Coenzyme Q10 is a fat-soluble nutrient that helps mitochondria (small structures in the cells) make energy. It is also an antioxidant that protects against cell damage. Coenzyme Q10 is sold as a supplement and used in the treatment of some heart disease, cancer, and other conditions. Also called ubiquinone and Q10, it is found in foods such as fatty fish, beef, soybeans, peanuts, and spinach. It is being studied in the prevention and treatment of heart disease, and in relieving the side effects of some cancer medications, such as statins and beta-blockers.
Several small placebo-controlled studies have reported that supplemental coenzyme Q10 improves exercise capacity and reduces chest pain (angina pectoris) in people with chronic stable heart failure. Coenzyme Q10 may work by enhancing the action of a-tocopherol to inhibit the oxidation of low-density lipoproteins in arterial walls.
In one study, supplementation with 600 mg of coenzyme Q10 taken 12 hours before angioplasty reduced the concentration of C-reactive protein (a marker of inflammation) and oxidative stress in patients after angioplasty compared to placebo. Coenzyme Q10 may help prevent the progression of atherosclerosis by increasing endothelium-dependent vasodilation and reducing vascular smooth muscle cell adhesion to the blood vessel wall (49).
A few small trials have reported that supplemental coenzyme MGQ10 improves cognitive function in people with early Parkinson’s disease, possibly by counteracting the decrease in activity of the mitochondrial electron transport chain in neurons. It has also been shown to slow the deterioration of movement disorder symptoms in animal models of Huntington’s disease, perhaps by improving mitochondrial function and limiting the accumulation of toxic waste products that cause cell death in these disorders (70).